Dehydration Contributes to Fibromyalgia Symptoms

Hormones that may be Affected by Hypothalamic Dysfunction           

The hypothalamus is the master gland controlling the activity of most other glands in the body.

This small gland coordinates a phenomenal portion of the body’s activity. The hypothalamus receives and transmits messages from the nervous system and hormonally through the circulatory system.

Because of its broad sphere of influence, the hypothalamus could be considered the homeostatic regulating center. It regulates appetite, monitors blood sugar, blood volume (fluid level within the circulatory system), and metabolism. It is the coordinating center for much of the autonomic nervous system. The autonomic nervous system is like our little robot that controls all of our unconscious functions including breathing, heartbeat and digestion.

Low Vasopressin (anti-diuretic hormone). 

This causes decreased ability to hold on to fluid resulting in frequent urination and increased thirst. 

Dehydration then occurs despite increased water intake.  Because vasopressin is also a stimulus for adrenocorticotropic hormone (ACTH) and adrenal function, low vasopressin could also result in decreased adrenal function.  Both dehydration and low cortisol (a hormone secreted by the adrenals) can increase the susceptibility to NMH.

“How do you tell who has the worst case of FMS or CFS?  By the size of their water bottle.”

Dehydration can cause many of the chronic symptoms seen in FMS and CFS including NMH, depression, excess body weight, high blood pressure, fatigue, low back and neck pain, and headaches.

Dehydration depletes the neurotransmitter serotonin. A reduction in serotonin is associated with insomnia, increased pain and depression and is a major cause of fibromyalgia!

From Dr. Batmanghelidj and his book “Your Body’s Many Cries for Water” comes the following;

“The human body is composed of 25% solid matter (the solute) and 75% water (the solvent). The brain tissue is said to consist of 85% water...It is the solvent-the water content-that regulates all functions of the body, including the activity of all the solutes (the solids) that are dissolved in it.

The disturbances in water metabolism of the body (the solvent metabolism) produces a variety of signals, indicating a “system” disturbance in the particular functions associated with water supply and its rationed regulation. Let me repeat, every function of the body is monitored and pegged to the efficient flow of water. “Water distribution” is the only way of making sure that, not only an adequate amount of water, but its transported elements, hormones, chemical messengers and nutrients first reach the more vital organs…

However, since water shortage in different areas of the body will manifest varying symptoms, signals and complications now labeled as disease, as soon as water is offered as a natural solution, people may think this could not be so!”

I recommend my patients drink pure water-half their weight in ounces on a daily basis.

The above material comes from my book “Treating and Beating Fibromyalgia and Chronic Fatigue Syndrome.”

You can read more about my book by clicking the link below-

http://store.drmurphreestore.com/trandbefiand1.html

What Your Doctor Won’t Tell You About IBS

  

What Your Doctor Won’t Tell You About IBS

How You Can Reverse IBS In As Few As 2 Weeks

An estimated 40 million Americans suffer with irritable bowel syndrome (IBS).

Some experts, recognizing that many go undiagnosed, suggest that irritable bowel syndrome (IBS) affects approximately 10–20% of the general population. The majority of patients I see for fibromyalgia suffer with IBS. 

Irritable bowel syndrome is characterized by a group of symptoms in which abdominal

pain or discomfort is associated with a change in bowel pattern, such as loose or more frequent bowel movements or diarrhea, and/or hard or less frequent bowel movements or constipation.

We know that gender plays a clear role, as more than 80 percent of IBS patients are

women between 20 and 55 years old.

The criteria for diagnosing IBS is based on the newly modified Rome criteria (Rome II criteria) as the presence for at least 12 weeks (not necessarily consecutive) in the preceding 12 months of abdominal

discomfort or pain that cannot be explained by a structural or biochemical abnormality and that has at least two of following three features:

(1) pain is relieved with defecation, and its onset is associated (2) with a change in the frequency of bowel movements (diarrhea or constipation) or (3) with a change in the form of the stool (loose,

watery, or pellet-like).

Some people with the disorder have constipation (IBS-C). Some have

diarrhea (IBS-D). And some alternate back and forth between constipation and diarrhea (IBS-A).

IBS symptoms result from what appears to be a disturbance in the interaction between the gut or intestines, the brain, and the autonomic nervous system that alters regulation of bowel motility

(motor function) or sensory function.

Research has shown that the cause of IBS is related to neuroendocrine- immune system dysfunction (brain and stomach hormones). This connection is largely mediated by the neurotransmitter or brain hormone known as serotonin. The brain and gut are connected through the neuroreceptors (hormone docking stations) for serotonin, 5-hydroxytriptamine-3 (5-HT3) and 5-hydroxytriptamine-4 (5-HT4).

These serotonin receptors regulate the perception of intestinal pain and the GI motility (contractions that move food through the intestinal tract). Therefore serotonin controls how fast or how slow food moves through the intestinal tract. In fact, there are more serotonin receptors in the intestinal tract than there are in the brain. Ninety percent of serotonin receptors are in the intestinal tract.

Research suggests that IBS patients have extra sensitive pain receptors in the gastrointestinal tract, which may be related to low levels of serotonin (another link to fibromyalgia). Decreased levels of serotonin may help explain why people with IBS are likely to be anxious, depressed or have fibromyalgia. Studies

show that 54–94% of IBS patients meet the diagnostic criteria for depression, anxiety, or panic disorder.

Restoring optimal levels of serotonin has been the focus of traditional drug therapy. Zelnorm, a 5-HT4 receptor agonist, was once hailed as “the drug” for IBS-c (IBS with frequent constipation), has

recently pulled from the market for its association with heart attacks and stroke. The percentage of patients taking Zelnorm that had serious and life-threatening side effects was 10 times higher than the

percentage of patients taking a placebo.

Even before this drug was recalled cardiovascular risks, many experts warned that this drug was dangerous for its other potential side effects including severe liver impairment, severe kidney impairment,

bowel obstruction, diarrhea, constipation, abdominal pain, headaches, abdominal adhesions, gallbladder disease, and back pain.

Antispasmodics (Levsin, Levsinex, Bentyl, Donnatal, etc.) are routinely prescribed for the treatment of IBS symptoms. 

Potential side effects include bloating; blurred vision; clumsiness; constipation; decreased sweating; dizziness; drowsiness; dry mouth; excessive daytime drowsiness ("hangover effect"); feeling of a whirling motion; headache; light-headedness; nausea; nervousness; rash; hives;

difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue agitation; confusion; diarrhea; difficulty focusing eyes; disorientation; exaggerated feeling of well-being;

excitement; fainting; fast or irregular heartbeat; hallucinations; loss of coordination; loss of taste; memory loss; muscle pain; pounding in the chest; severe or persistent trouble sleeping; trouble

urinating; unusual weakness; very slow breathing; vision changes; vomiting.

Using potentially dangerous drugs to reduce symptoms, while ignoring natural and often more effective approaches is typical of what is wrong with “cookbook” (symptom-focused)

medicine.

        Reversing IBS With Nutritional Therapy

 I find that IBS usually disappears rather quickly once my patient’s correct their poor eating habits (increase fiber, reduce simple sugars, caffeine and junk foods), uncover any hidden allergies when

present, including gluten intolerance (Celiac disease), boost optimal stress coping chemicals (serotonin, magnesium, B-vitamins, etc.), restore bowel ecology (probiotics), and take the right digestive enzymes with their meals.

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5HTP

To boost serotonin levels I recommend patients take, the amino acid responsible for making serotonin, known as 5-hydroxytryptophan (5HTP). 5HTP along with the right vitamins and minerals, is responsible for making serotonin.

Patients should take 300-400mg a day with food or if have fibromyalgia and suffer with poor sleep, start with 100mg taken on empty stomach 30 minutes before bed with 4 ounces of grape juice and increase by 100mg each night up to 300mg.

 Digestive enzymes

Most digestion and absorption takes place in the small intestine and is regulated by pancreatic enzymes (digestive) and bile. The pancreas aids in digestion by releasing proteolytic enzymes, which help break

down proteins into amino acids. Natural digestive enzymes are found in raw fruits and vegetables. Processed foods are usually devoid of digestive enzymes.

Over consumption of these processed foods can lead to digestive enzyme deficiencies. This may then lead to malabsorption and or intestinal permeability syndrome (bloating, gas, indigestion, diarrhea,

constipation, and intestinal inflammation). To ensure proper digestion and absorption, I recommend taking pancreatic enzymes with each meal.

For stubborn IBS symptoms, I recommend using a high dose, pharmaceutical grade, pure 8X (100% stronger than most over the counter digestive enzymes).

Magnesium

I always recommend people take a good optimal daily allowance

multivitamin/mineral formula. Patients with IBS have depleted their stress-coping chemicals (serotonin, magnesium, and vitamins) and this not only leads to IBS but also prevents them from overcoming IBS.

It is a vicious cycle that can only be broken by taking adequate amounts of essential vitamins, minerals and other nutrients I’ve already mentioned above. The mineral magnesium, which is involved in over 300 bodily processes, is particularly important for reversing the symptoms of IBS-c and IBS-A.

Magnesium helps relax the smooth muscle of the colon (natural laxative) allowing normal bowel movements. While a diet high in nutritious fiber is important, magnesium is even more important. A

magnesium deficiency not only causes constipation but can also lead to heart disease, mitral valve prolapse (MVP), depression, anxiety, chronic muscle pain, headaches, migraines, fatigue, and many other unwanted health conditions. Those with IBS-c may need up to 1,000mg of

magnesium each day. While those with IBS-d, may need less than 500mg.

I recommend patients begin with 500mg of magnesium a day, preferably taken in a multivitamin formula.

Probiotics

The human intestines are inhabited by billions of beneficial bacteria. These bacteria, which are mostly located in the colon, aid in digestion by fermenting substances that were not digested in the small

intestine and by breaking down any remaining nutrients. A healthy intestinal tract contains some 2-3 lb. of bacteria and other microorganisms, such as yeast, that normally don’t cause ay health

problems.

However, when the intestinal tract is repetitively exposed to toxic substances (antibiotics, steroids, NSAIDs, etc.), these microorganisms begin to proliferate and create an imbalance in the bowel flora.

Harmful organisms like yeast and some normally dormant bacteria, begin to overtake the good bacteria. This is known as intestinal dysbiosis.

IBS and small-intestinal bacterial overgrowth may share similar symptoms. One study showed that 78% IBS participants had small-intestinal bacterial overgrowth. To aid in digestion and prevent intestinal dysbiosis, patients with IBS should take probiotics (Lactobacillus and Biidobacterium) on a daily basis.

I recommend taking a high dose (9 billion strong), pure, enteric coated probiotic formula once a day on an empty stomach for 2-3 months.

This approach isn’t guaranteed to solve every case of IBS. However, in

the majority of my patients, their IBS symptoms are usually gone within two weeks.